Professor Hiroshi Takayanagi

I was born in 1965 and graduated from the Faculty of Medicine, The University of Tokyo in 1990.  I was initially trained as an orthopaedic surgeon and rheumatologist in the Department of Orthopaedic Surgery, The University of Tokyo.  I began my basic research career in 1996 and discovered that bone destruction in arthritis is attributable to the enhanced expression of osteoclast differentiation factor, RANKL, in 2000.  I was awarded Ph.D in 2001 and became Assistant Professor at the Department of Immunology, The University of Tokyo.  I studied the regulation of bone metabolism by the immune system and explored the interdisciplinary field, osteoimmunology.  For the period from 2003 through 2012, I fulfilled responsibilities as a Professor at Tokyo Medical and Dental University.  In 2012, I was promoted to Professor, Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo.

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