Assoc Prof Natalie Sims

Assoc. Prof. Natalie Sims directs the Bone Cell Biology and Disease Unit at St. Vincent’s Institute and is an NHMRC Senior Research Fellow and Principal Research Fellow at The University of Melbourne. She completed her PhD in 1995 at the University of Adelaide, and started her own laboratory in Melbourne in 2001 after postdoctoral studies at the Garvan Institute (Sydney) and Yale University. She defined the roles of Oncostatin M, Cardiotrophin 1, and Leukemia Inhibitory Factor on the development and maintenance of the skeleton, using genetically altered mouse models and in vitro systems. She has worked closely with Prof TJ Martin on developing theories of bone cell communication, particularly with respect to the concept of “coupling”. Her current work continues to focus on paracrine control of the skeleton, particularly the way parathyroid hormone, IL-6 and STAT1/3 signalling influence bone formation and destruction. She has >100 publications and review articles. Dr Sims is a board member of the American Society for Bone and Mineral Research. She is a Senior Editor of the journal Bone. Her work has been recognised by the ASBMR Fuller Albright Award (2010) and the International Bone and Mineral Society Herbert A Fleisch Award (2013). 

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